Vascular Medicine Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study
نویسندگان
چکیده
Timothy P. Murphy, MD; Donald E. Cutlip, MD; Judith G. Regensteiner, PhD; Emile R. Mohler, MD; David J. Cohen, MD; Matthew R. Reynolds, MD, MSc; Joseph M. Massaro, PhD; Beth A. Lewis, PhD; Joselyn Cerezo, MD; Niki C. Oldenburg, Dr. PH.; Claudia C. Thum, MA; Suzanne Goldberg, MSN; Michael R. Jaff, DO; Michael W. Steffes, MD; Anthony J. Comerota, MD; Jonathan Ehrman, PhD; Diane Treat-Jacobson, RN, PhD; M. Eileen Walsh, RN, PhD; Tracie Collins, MD; Dalynn T. Badenhop, PhD; Ulf Bronas, PhD; Alan T. Hirsch, MD; for the CLEVER Study Investigators
منابع مشابه
Supervised Exercise Versus Primary Stenting for Claudication Resulting From Aortoiliac Peripheral Artery Disease: Six-Month Outcomes From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study
Claudication is the most common ischemic symptom of peripheral artery disease (PAD), affecting approximately 30% of these patients and limiting pain-free walking in over 2 million Americans. There are 3 treatments available to improve these symptoms, including claudication pharmacotherapy (cilostazol), supervised exercise, and endovascular revascularization, but little data comparing their rela...
متن کاملSupervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study.
BACKGROUND Claudication is a common and disabling symptom of peripheral artery disease that can be treated with medication, supervised exercise (SE), or stent revascularization (ST). METHODS AND RESULTS We randomly assigned 111 patients with aortoiliac peripheral artery disease to receive 1 of 3 treatments: optimal medical care (OMC), OMC plus SE, or OMC plus ST. The primary end point was the...
متن کاملCost‐Effectiveness of Supervised Exercise, Stenting, and Optimal Medical Care for Claudication: Results From the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Trial
BACKGROUND Both supervised exercise (SE) and stenting (ST) improve functional status, symptoms, and quality of life compared with optimal medical care (OMC) in patients with claudication. The relative cost-effectiveness of these strategies is not well defined. METHODS AND RESULTS The Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) study randomized patients with claudicati...
متن کاملSupervised exercise, stent revascularization, or medical therapy for claudication due to aortoiliac peripheral artery disease: the CLEVER study.
BACKGROUND Treatment for claudication that is due to aortoiliac peripheral artery disease (PAD) often relies on stent revascularization (ST). However, supervised exercise (SE) is known to provide comparable short-term (6-month) improvements in functional status and quality of life. Longer-term outcomes are not known. OBJECTIVES The goal of this study was to report the longer-term (18-month) e...
متن کاملEditor’s Perspective Lessons Learned from Recent Randomized Clinical Trials for Intermittent Claudication
It is well recognized that lower extremity peripheral arterial disease (PAD) is highly prevalent and results in significant cardiovascular mortality akin to cardiovascular disease.1 Among patients with PAD there is a broad range of clinical manifestations, with a third of patients having typical intermittent claudication (IC). The symptoms of lower extremity PAD, even in a stable nonlimb threat...
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تاریخ انتشار 2011